Asymmetric periflexural exanthem of childhood

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Asymmetric periflexural exanthem of childhood
a)Unilateral laterothoracic exanthem, starts on the lateral aspect of trunk near the axilla b)presence of perisudoral lymphocytic infiltrates

Asymmetric periflexural exanthem of childhood (APEC) (also known as unilateral laterothoracic exanthem) is a rare, self-limited and spontaneously resolving skin rash of the exanthem type with unknown cause that occurs in children.[1] It occurs primarily in the late winter and early spring, most common in Europe, and affecting girls more often than boys.[2]: 400 [3]

It is probably viral,[4] but no virus has yet been associated with the condition.

See also


  1. Arun, B; Salim (May–June 2010). "Transient linear eruption: asymmetric periflexural exanthem or blaschkitis". Pediatr Dermatol. 27 (3): 301–302. doi:10.1111/j.1525-1470.2010.01143.x. PMID 20609153.
  2. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  3. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1227–8. ISBN 978-1-4160-2999-1.
  4. Zawar VP (2003). "Asymmetric periflexural exanthema: a report in an adult patient". Indian J Dermatol Venereol Leprol. 69 (6): 401–4. PMID 17642951. Archived from the original on 2020-11-26. Retrieved 2021-05-28.

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