|Trade names||Camoquin, others|
|Defined daily dose||not established|
|(what is this?)|
Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria. It is a fixed-dose combination of artesunate and amodiaquine. Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. It is taken by mouth.
Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough. Safety in pregnancy is not clear; however, the medication may be used if others are not possible. It is believed to be safe for use during breastfeeding. Artesunate and amodiaquine are both antimalarial medication; however, work by different mechanisms.
Artesunate/amodiaquine was commercially launched in 2007. It is on the World Health Organization's List of Essential Medicines. Artesunate/amodiaquine is available as a generic medication. The wholesale cost in the developing world is about US$0.85 to US$1.52 for a course of treatment. As of 2014 it is not commercially available in the United States or United Kingdom.
Early clinical trials showed that a once-a-day dosage was effective. It was subsequently shown to be equally effective as artemether/lumefantrine, although it is likely to be more effective in the field due to its simpler once-a-day dosage compared to artemether/lumefantrine twice-per-day dosage.
The defined daily dose is not established. For those who weight more than 35 kg the dose is 200/540 mg one a day, for those who weight 18 to 35 kg the dose is 100/270 mg once a day, for those who weight 9 to 18 kg the dose is 50/135 mg once per day, and for those who weight 4.5 to 9 kg the dose is 25/67.5 mg once per day. Treatment is for three days.
Society and culture
Artesunate/amodiaquine was commercially launched in 2007 as an affordable treatment for malaria, devised by DNDi in partnership with Sanofi-Aventis. ASAQ was handed over to the MMV Access and Product Management Team in May 2015.
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