Angelicin synthase

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Angelicin synthase
Identifiers
EC no.1.14.13.115
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

Angelicin synthase (EC 1.14.13.115, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase.[1] This enzyme catalyses the following chemical reaction:

(+)-columbianetin + NADPH + H+ + O2 angelicin + NADP+ + acetone + 2 H2O

Angelicin synthase is a P450 monooxygenase enzyme.

References

  1. ^ Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F (February 2009). "Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis". The Journal of Biological Chemistry. 284 (8): 4776–85. doi:10.1074/jbc.M807351200. PMID 19098286.

External links