Anethole trithione

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Anethole trithione
Skeletal formula of anethole trithione
Ball-and-stick model of the anethole trithione molecule
Clinical data
ATC code
  • 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.007.754 Edit this at Wikidata
Chemical and physical data
Molar mass240.35 g·mol−1
3D model (JSmol)
  • S=C\2SS/C(c1ccc(OC)cc1)=C/2
  • InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3 checkY

Anethole trithione, anetholtrithione, or anetholtrithion (JAN) is a drug used in the treatment of dry mouth. It is listed in the U.S. National Cancer Institute's Dictionary of Cancer Terms as being studied in the treatment of cancer.[1] Anethole trithione is an organosulfur compound, specifically, a dithiole-thione derivative.[2]

Brand names

  • Felviten
  • Halpen
  • Hepasulfol - Franco-Indian Pharmaceuticals
  • Heporal
  • Mucinol - Sanofi-Aventis
  • Sialor - Paladin Laboratories; Pharmascience; Solvay; Zuoz Pharma
  • Sonicur - Solvay
  • Sulfarlem - Solvay; Aguettant; Edward Keller; Sanofi-Aventis
  • Sulfarlem S - EG Labo
  • Tiopropen
  • Tiotrifar

See also


  1. ^ Anetholtrithione entry in the public domain NCI Dictionary of Cancer Terms. Retrieved September 13, 2008.
  2. ^ Christen MO (1995). "Anethole dithiolethione: biochemical considerations". Methods in Enzymology. 252: 316–23. doi:10.1016/0076-6879(95)52034-1. PMID 7476368.