File:Pleuromutilin proposed cyclisation mechanism.png
Jump to navigation
Jump to search
Size of this preview: 800 × 552 pixels. Other resolutions: 320 × 221 pixels | 640 × 442 pixels | 1,024 × 707 pixels | 1,280 × 883 pixels | 2,560 × 1,766 pixels | 3,074 × 2,121 pixels.
Original file (3,074 × 2,121 pixels, file size: 398 KB, MIME type: image/png)
Summary
| Description |
English: Proposed biosynthetic pathway of pleuromutilin. The left part of the scheme is representing a general biosynthetic approach for Geranylgeranyl pyrophosphate (GGPP). The follwoing cyclisation steps to the pleuromutilin tricyclic core will be provided by class II and class I terpene synthase domain of Pl-cyc. Final catalytic, stereospecific hydroxylation at C-11 and C-3, regiospecific oxidation of the 3-hydroxy group to a keton, acetyl-group-transfers OH-14 and final hydroxylation at the α-acetyl position will lead to pleuromutilin. |
| Date | |
| Source | Own work |
| Author | Ameisensoldat |
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 16:21, 24 May 2021 | | 3,074 × 2,121 (398 KB) | commons>Ameisensoldat | Cross-wiki upload from en.wikipedia.org |
File usage
There are no pages that use this file.
