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Description13256 2016 964 Fig1 HTML.jpg	English: The γ-glutamyl cycle. Step 1: Glutathione synthetase deficiency induces a decrease in the levels of glutathione and an increase of γ - glutamyl cysteine. Step 2: Glutathione deficiency induces negative feedback in the γ-glutamyl-cysteine synthetase. Step 3: 5-oxoproline is produced by γ-glutamyl cyclotransferase from γ-glutamyl-cysteine. Step 4: 5-oxoproline is converted to L-glutamate by the 5-oxoprolinase, which is quickly saturated
Date	2016
Source	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918112/
Author	Charlotte Lanoy and Yves Bouckaert

{{subst:Custom license marker added by UW}} https://creativecommons.org/licenses/by/4.0/ Attribution 4.0 International (CC BY 4.0)

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